Winona
PartnerOne bundled cash price
- Care price
- $0 membership; product pricing
- Medication
- Included with selected products
- Typical first 90 days
- $372 for pill + progesterone; 4 charges in 90 days28-day billing; verify product and checkout
By The HRT Index — an independent comparison resource for HRT telehealth providers · Last verified:
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This guide covers online HRT for menopause and perimenopause. Men’s testosterone therapy (TRT) and gender-affirming HRT have different costs, rules, and lab needs — and testosterone is a Schedule III controlled substance in the U.S. that always requires a prescription and a clinician’s evaluation. We cover those on separate pages.
How much does online HRT cost? Here’s the short answer, and then we’ll show you the real number for your exact situation.
Online HRT for menopause usually costs $35 to $250 a month for the care part — the visit or membership — plus the price of your medication. Most women paying cash land somewhere between $80 and $150 a monthonce everything is added up. Your real number comes down to four things: whether you use insurance, which hormone you take, whether the provider includes your medication or sends it to a pharmacy, and whether you need lab work. If you have a PPO plan, your cheapest path is often through an in-network provider like Midi Health. If you’re paying cash, an all-in plan like Winona or a low-care-fee plan like Sesame is usually where to start.
That last part — “everything added up” — is exactly where most price guides leave you hanging. They give you a range like “$10 to $500” and call it a day. Below, we’ve done the spreadsheet work for you: real prices for every major online HRT provider, what’s included and what’s not. See also our self-pay cost breakdown and best subscription comparison.
Cost-first starting point
Start with the payment model that matches your situation. Exact cost still depends on eligibility, deductibles, medication, labs, and the provider's current checkout terms.
The calculator separates what may be due now, cash charged during the first 90 days, and the 90-day treatment-equivalent cost. No email is required.
Calculate my HRT cost →Need help with provider, medication, or eligibility fit instead? Use Find My HRT Path.
Compare what may be due up front, during the first 90 days, and over the first year. No email required.
Calculate my HRT cost →| If this sounds like you | Start here | Why |
|---|---|---|
| I have PPO or employer insurance | Midi Health | Midi is in-network with many PPO plans; if yours is included you may owe only a copay |
| I want one flat price, everything handled | Winona | One published product price with selected medication and shipping included; verify current terms |
| I want a low care fee and to fill meds my own way | Sesame | $59/month covers ongoing care, messaging, and basic labs when necessary; you fill medication at your pharmacy |
| I want a big-name brand with app-based care | Hers | Recognizable brand, pill or patch, starts at $79/month |
| I only need vaginal estrogen | Alloy or Wisp | Local-only treatment usually costs less than full-body HRT |
| I’m not sure yet | Take the 60-second quiz | Get a personalized plan before you choose |
I have PPO or employer insurance
Start here: Midi Health
Midi is in-network with many PPO plans; if yours is included you may owe only a copay.
I want one flat price, everything handled
Start here: Winona
One published product price with selected medication and shipping included; verify current terms.
I want a low care fee and to fill meds my own way
Start here: Sesame
$59/month covers ongoing care, messaging, and basic labs when necessary; you fill medication at your pharmacy.
I want a big-name brand with app-based care
Start here: Hers
Recognizable brand, pill or patch, starts at $79/month.
I only need vaginal estrogen
Start here: Alloy or Wisp
Local-only treatment usually costs less than full-body HRT.
Online HRT for menopause typically costs $35 to $250 a month for the care part (a visit or membership), plus the cost of your medication, which is sometimes included and sometimes billed separately. Insurance-based care can cost as little as a copay, while a self-pay specialist visit can run up to $250 for the first appointment. The most useful number is not the monthly headline price — it’s your first-90-day total.
Here’s the thing nobody tells you up front: online HRT is almost always two costs, not one.
When you only look at the care cost, a “$59 a month” plan can look cheaper than an “$89 a month” plan — even when the $89 plan is actually cheaper once you add the medication. That’s the trap.
The first three months typically cost more than your steady monthly rate. Why? Setup. You’re paying for a first visit (often pricier than follow-ups), maybe lab work, your first medication fill, and in a lot of cases a three-month billing cycle that charges you for 90 days at once.
So here’s the simple formula we use across this whole page:
The first-90-day formula:
First-90-day cost = consult or membership fees + any follow-up fee + 3 months of medication + labs (if ordered) + shipping or pharmacy costs
Run that math before you sign up, and the surprises disappear.
Provider prices only make sense when you separate the care fee from the medication, the labs, and the insurance model. As of September 1, 2026, monthly care costs range from about $35 a month(Evernow’s annual plan) to $250(Midi’s self-pay first visit), and flat cash-pay programs like Winona start around $89/month with medication and shipping included.
How to read this table:All prices are self-pay (cash) unless noted. “First-90-day” is the care/medication math you can expect for a typical starting plan. “Verified” means we confirmed it on the provider’s public page. “Confirm at checkout” means the price can change based on intake, eligibility, or your plan, so treat it as a strong estimate, not a locked number.
One bundled cash price
Brand + app-based care
Low care fee + own pharmacy
Commercial insurance / PPO
Posted FDA-approved product prices
Low membership sticker price
Membership + shipped medication
Consult + local pharmacy
Specifically wants compounded care
Partner links may earn The HRT Index a commission; your price is unchanged. Direct links are not paid placements. All prices are estimates, not a guarantee of eligibility or amount due today.
Insurance can lower your online HRT cost, but only if the provider bills your plan andyour medication is covered. Some providers bill insurance for visits, some don’t bill insurance at all, and most leave the medication to your pharmacy benefits. As of September 1, 2026, Midi Health is in-network with many PPO plans, while Winona, Hers, and Sesame are cash-pay and do not bill insurance for their service.
If you have a PPO or employer plan, this is usually your cheapest door. Midi’s own pricing page says it’s in-network with many PPO plans; if yours is covered, your visit may cost only a copay — though deductibles and coinsurance can still apply. If you pay cash instead, Midi charges $250 for a first visit and $150 for follow-ups. Your medication is filled separately at a pharmacy.
A fair warning, plainly stated:if you don’t have commercial insurance, Midi is one of the priciercash options because of that $250 first visit. If you’re paying cash and want the lowest price, Midi is not your pick — skip to the without-insurance section. But if your PPO is accepted, Midi flips to one of the cheapest and most thorough routes there is: real menopause-trained clinicians, billed through your insurance.
A patient on Midi’s website describes signing up and getting “a visit the next day,” with the prescription called in the same day. We share notes like this only to show what the sign-up experience is like — they’re published by the provider, they don’t prove typical medical results, and individual experiences vary.
On Medicaid or Medi-Cal? Midi can’t help — see our low-cost cash options instead.
Evernow runs a membership ($49/month, or about $35/month on the annual plan) and also offers one-time virtual visits it describes as insurance-eligible. Medication is separate, billed at your pharmacy, where your own insurance can apply. Evernow.com →
Winona, Hers, Sesame, Pandia, and Wisp are cash-pay for their service. Sesame states plainly that it does notbill health insurance for its subscription — though your medication or labs may still be covered through your own plan and pharmacy. That’s not a bad thing. Cash-pay means a predictable price and no claim denials. It just means the savings come from shopping smart, not from your insurance card.
Be careful here — this is where people get a nasty surprise:
If you’re on Medicare or Medicaid, your cheapest path is usually a covered visit with your own doctor plus a covered generic — not a cash subscription.
The cheapest legitimate online HRT without insurance is usually a low-cost membership or consult plus a generic hormone filled at a discount pharmacy. Generic estradiol tablets can be $20 or less for a 90-day supply with a GoodRx coupon, and generic estradiol patches often run about $20–$40 a month with a coupon. The key truth: the lowest advertised price is not always the lowest total once you add medication and labs.
We’ll say the quiet part out loud, because it’s what makes this page worth trusting.
If you have insurance and want the rock-bottom price:
The cheapest route isn’t a subscription at all. It’s a covered visit (a copay, often $0–$30) plus generic estradiol, which most plans cover for $10–$30 a month. That can be under $50 for a full 90 days. Do that.
If you’re paying cash and want the lowest sticker:
A low membership like Evernow (from $35/month on the annual plan, $49 month-to-month) plus a cheap generic is hard to beat. GoodRx lists generic estradiol at around $84 for the most common version — about 73% off the roughly $314 average retail price — and generic estradiol tablets can be $20 or less for 90 days. Mark Cuban Cost Plus Drugs is another transparent cash pharmacy worth checking.
So why would anyone pay $89 or $99 a month instead?
Because cheapest and easiest are not the same thing.The flat-fee programs aren’t trying to win on price. They win on simplicity: no insurance phone calls, no chasing a pharmacy, medication shipped to your door, unlimited messaging with a clinician, and a more predictable charge with fewer pharmacy surprises. For a lot of women, paying a little more to never think about it again is the better deal. Only you can decide which you value more.
The most common surprise costs in online HRT are medication (often billed separately), lab work ($50–$200 if it’s not covered), progesteroneas an add-on (about $10–$40 a month if you need it), and annual-plan lock-ins. Sesame states that medication is not included in its monthly subscription. Always confirm exactly what the price covers before you pay.
Here’s where the “$59 a month” magic disappears:
| Hidden cost | Who gets surprised | Typical add | How to dodge it |
|---|---|---|---|
| Medication billed separately | Sesame, Midi, Wisp, Pandia, Evernow | The full drug price | Ask: “Is medication included, or do I pay a pharmacy?” Then price it on GoodRx. |
| Progesterone as a second charge | Anyone with a uterus taking estrogen | ~$10–$40/mo | Ask if your quote is estrogen-only. If you have a uterus, you usually need progesterone too. |
| Lab work | Providers that don’t bundle labs | ~$50–$200 if not covered | Pick a provider that includes basic labs (like Sesame), or use insurance for labs. |
| Annual-plan lock-in | The lowest “from” prices | — | Read the commitment length before you fall for the headline price. |
| Shipping | Some shipped-product plans | Varies | Confirm shipping is included before checkout. |
Medication billed separately
Who: Sesame, Midi, Wisp, Pandia, Evernow
Typical add: The full drug price
Ask whether medication is included or filled at a pharmacy, then price it on GoodRx.
Progesterone as a second charge
Who: Anyone with a uterus taking estrogen
Typical add: ~$10–$40/mo
Ask if your quote is estrogen-only; you usually need progesterone if you have a uterus.
Lab work
Who: Providers that don't bundle labs
Typical add: ~$50–$200 if not covered
Choose a provider that includes basic labs, or use insurance for labs.
Annual-plan lock-in
Who: The lowest “from” prices
Typical add: —
Read the commitment length before choosing the headline price.
Shipping
Who: Some shipped-product plans
Typical add: Varies
Confirm shipping is included before checkout.
The lowest advertised price is often not the lowest total cost.
A $59-a-month service can still cost more than a higher all-in plan if your medication or labs are pricey. You can pick a low-cost care route and still shop the medicationthrough insurance, GoodRx, or your local pharmacy if the provider lets you. That one move — splitting care from medication — is how you avoid overpaying.
Screenshot this. Ask every provider these five things and you’ll never get surprised:
If a provider can’t answer those clearly, treat the advertised price as incomplete.
See what to verify before you pay →Lab work can be included, billed to insurance, or paid out of pocket — and that choice can swing your first-90-day total by $50 to $200. Some providers fold basic labs into the price when a clinician orders them; others send you to a lab and you pay separately. Whether you even need labs depends on your symptoms and history, and that’s a clinical decision, not a sales one.
The takeaway: when you compare two providers, ask whether labs are included, billed to insurance, or extra. A plan that looks $40 cheaper can lose that edge the moment a $150 lab bill lands.
Your hormone type can change the total more than the provider fee does. Generic estradiol pills are the cheapest ($20 or less for a 90-day supply with a GoodRx coupon), generic patchesrun about $20–$40 a month with a coupon, and brand-name estradiol can cost several times more — GoodRx lists the most common version at roughly $314 average retail before coupons. Switching from a brand to its FDA-approved generic is usually the single biggest saving you can make.
Quick definitions: Estradiol is the main form of estrogen used to treat menopause symptoms. Progesterone is added to protect the lining of the uterus if you still have one. Systemic HRT treats your whole body (hot flashes, night sweats). Vaginal (local) estrogen treats dryness and bladder symptoms only.
| Form | Typical cost (verified examples) | How to save |
|---|---|---|
| Generic estradiol pill | $20 or less for a 90-day supply with a GoodRx coupon; about $10–$30/mo with insurance | Use the generic; coupon it |
| Generic estradiol patch | About $20–$40/mo with a GoodRx coupon | Coupon cards; ask about manufacturer copay cards |
| Brand-name estradiol (e.g., Vivelle-Dot) | GoodRx ~$314 average retail; about $84 with a coupon | Switch to the FDA-approved generic |
| Progesterone (micronized) | Roughly $10–$40/mo | Generic; remember it’s often a separate charge |
| EstroGel (brand gel) | ~$290/mo cash (GoodRx); ~$35/mo with manufacturer savings card. Alloy lists FDA-approved estradiol gel at $69.99/mo | Savings card, or a telehealth gel plan |
| Premarin (brand) | Pricier brand; manufacturer savings programs can bring it to roughly $25–$30/mo for eligible patients | Savings card; ask about a generic estradiol alternative |
| Vaginal estrogen cream | Generic as low as about $29 with a GoodRx coupon; brand creams cost much more | Generic; copay card |
| Vaginal ring | GoodRx notes some estrogen options exceed $800 for a 90-day ring | Compare the per-month cost vs. other forms |
Generic estradiol pill
$20 or less for a 90-day supply with a GoodRx coupon; about $10–$30/mo with insurance.
Use the generic; coupon it.
Generic estradiol patch
About $20–$40/mo with a GoodRx coupon.
Use coupon cards and ask about manufacturer copay cards.
Brand-name estradiol (e.g., Vivelle-Dot)
GoodRx ~$314 average retail; about $84 with a coupon.
Switch to the FDA-approved generic.
Progesterone (micronized)
Roughly $10–$40/mo.
Use generic; remember it's often a separate charge.
EstroGel (brand gel)
~$290/mo cash; ~$35/mo with a manufacturer savings card. Alloy lists FDA-approved estradiol gel at $69.99/mo.
Use a savings card, or compare a telehealth gel plan.
Premarin (brand)
Pricier brand; eligible patients may use manufacturer savings programs.
Ask about a savings card or FDA-approved generic estradiol.
Vaginal estrogen cream
Generic as low as about $29 with a GoodRx coupon; brand creams cost much more.
Compare generic and copay-card prices.
Vaginal ring
Some estrogen options exceed $800 for a 90-day ring.
Compare the per-month cost with other forms.
If your only issue is vaginal dryness or bladder symptoms, you may not need full-body HRT at all. A local vaginal estrogenroute — like Alloy’s vaginal cream around $39.99/month or Wisp’s from $20— is often far cheaper than a systemic plan. Don’t let a provider funnel you into a bigger bundle than you need. See our vaginal estrogen guide.
In April 2026, Reuters reported that Hims & Hers said it had secured a steady supply of estrogen patches even as some pharmacies reported shortages — and Reuters noted the FDA had not formally listed estrogen patches as in shortage at that time. Patch availability and price can vary by pharmacy right now, so if you want a patch, confirm your provider can actually fill it before you commit.
Cost matters — but don’t pick a hormone type by price alone. The right form depends on your symptoms, your medical history, whether you have a uterus, your risk factors, and your preferences, and that’s a decision to make with a licensed clinician. Use price to narrow your options, not to make the final call.
Sometimes — but not automatically, and it’s usually not covered by insurance. The FDA states that compounded drugs are not FDA-approved, and that it does not have evidence that compounded “bioidentical” hormones are safer or more effective than FDA-approved hormone therapy. FDA-approved estradiol and progesterone are widely covered by insurance and often cost less that way.
The cost angle:compounded-focused programs (like Oestra) can be simple to buy with a flat cash price, but because insurance usually won’t touch them, your total can end up higher than an FDA-approved generic you run through your plan. If budget is your top concern, an FDA-approved generic is usually the smarter buy. (For reference: Winona offers FDA-approved options, including its estrogen tablets, as well as compounded creams; Alloy’s listed products are FDA-approved; Oestra is compounded.)
See also: FDA-approved vs. compounded HRT explained.
There’s no single “cheapest” winner — the best value depends on your situation. Midi is usually cheapest if you have a PPO. Winona offers the simplest flat all-in price (from $89/month). Sesame has a low care fee with medication billed separately ($59/month). And insurance plus a generic is often the lowest total of all.
You came in with the cheapest possible card in your pocket. Use it. Midi bills most PPO plans, so you may owe only a copay for menopause-specialized care from a clinician who does this all day. (Not for Medicaid/Medi-Cal patients, and not covered by Medicare.) See our Midi review.
Check Midi coverage in your state →This is the “I don’t want to think about it” pick, and it’s a good one. One monthly price, medication included, free shipping, unlimited follow-ups, and 24/7 messaging with a doctor — Winona’s most popular plan (estrogen cream with progesterone) is $89/month, with tablets from $54 and patches from $149. Winona offers FDA-approved options (including its estrogen tablets) as well as compounded creams, so you can choose the route that fits — just know which one you’re getting. See our Winona review.
See current Winona pricing and availability →Partner link: we may earn a commission; your price is unchanged.
Sesame’s $59/monthmenopause subscription includes same-day visits, basic lab work when needed, and unlimited messaging — then you fill your medication at your pharmacy, where a GoodRx coupon often keeps it cheap. Great for women who want support but want to control the drug cost themselves. (Just remember: the $59 does not include the medication.) See our Sesame review.
See what Sesame’s menopause plan includes →Partner link: we may earn a commission; your price is unchanged.
Hers is the recognizable option, with estradiol pills from $79/month and patch kits from $134/month on a 12-month plan, plus app-based care. Hers is not available in all 50 states, so confirm your state during intake. For perimenopause specifically, note that hormone therapies are not FDA-approved to treat perimenopausebut may be prescribed off-label for perimenopausal symptoms when a provider decides it’s appropriate (Hers). Best if brand familiarity and a polished app matter to you more than the absolute lowest price. See our Hers review.
Check Hers availability in your state →Partner link: we may earn a commission; your price is unchanged.
Oestra is a compounded subscription reported at $199/month for the first six months, then $99.50/month, not covered by insurance but HSA/FSA-eligible, with free shipping. It belongs here as a specific-model choice, not a budget pick — and remember the FDA notes above: the finished compounded product is not FDA-approved.
Take the quiz to see if Oestra fits →Online HRT may not be the right first step if you have unexplained vaginal bleeding, a known or suspected hormone-sensitive cancer, a history of blood clots or stroke, liver disease, or a possible pregnancy. These situations usually need an in-person evaluation first.
We’d rather lose you here than steer you wrong. Please talk to a doctor in person first if any of these apply to you:
None of this means HRT is off the table for you — it just means your starting point should be a clinician who can examine you, not an online intake form. Sources: FDA · DailyMed estradiol prescribing information.
We checked each provider’s public pricing pages and provider pages, cross-referenced medication costs against GoodRx and Mark Cuban Cost Plus Drugs, and reviewed FDA and FTC guidance through September 1, 2026.
What we confirmed on public pages:
What we could not lock down (so confirm it yourself):
The HRT Index is the independent menopause-HRT decision resource for women telehealth providers. Some links are affiliate links, which means we may earn a commission if you use them. Our rankings are based on verified fit, pricing, medication model, insurance details, and trade-offs — never on which company pays us more.
Prices and policies change. We re-check top-provider pricing monthly and the full dataset quarterly, and we update the “Last verified” date when we do.
Take our free 60-second matching quiz. No email needed.
Start the quiz →Next step
Start with the calculator if cost is the decision. Use Find My HRT Path instead if provider fit, medication form, or eligibility is the bigger question.